I dont know if ClockWise has the same problem.
But in your case, leesm0218, you need to add the client id of your developer application ( https://dev.twitch.tv/dashboard/apps ) in the header of your request.
I not really familiar with python, but in php you can add it this way:
$ch = curl_init();
curl_setopt_array($ch, array(
CURLOPT_HTTPHEADER => array(
'Client-ID: ' . "[[YOUR CLIENT ID]]"
),
CURLOPT_RETURNTRANSFER => true,
CURLOPT_URL => "[[URL]]"
));
$output = curl_exec($ch);