The V5 API offers a neat call to set a lot of things of a channel:
It’s more or less a simple HTTP PUT call.
I don’t do Python, but the code should be fairly easy.
However, being a privileged call, you need an OAuth token for the channel you want to set values for, you can read up on that here:
It looks like a lot to swallow, at first, but it’s actually easier than it seems.