TMI.js is a great start for basic stuff, but unfortunately has fallen far behind on updates for the new features (such as gifted subs). Personally I’ve started using Twitch-js https://github.com/marcandrews/twitch-js for my Node app, very similar to TMI.js but much more up to date. If all you need is reading/responding to chat messages though, they’ll do that job equally well.
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